Scopolamine Powder

Scopolamine Analytical Reference Standard

A tropane alkaloid reference material, chemically designated as (—)-Scopolamine or 6-beta,7-beta-epoxy-1-alphaH,5-alphaH-tropan-3-alpha-yl (S)-tropate, supplied exclusively for laboratory research, forensic analysis, and pharmaceutical quality control applications. Scopolamine Analytical Reference Standard | CAS 51-34-3 | Pharmaceutical Reference Material for Laboratory Research

What is Scopolamine

Scopolamine, also known as hyoscine, is a naturally occurring tropane alkaloid derived from plants of the Solanaceae family, with the molecular formula C17H21NO4 and a molar mass of 303.35 g/mol. This analytical reference standard is supplied for legitimate scientific research applications including chromatographic method development, forensic toxicology screening, pharmaceutical quality control analysis, and alkaloid metabolism studies. As a characterized reference material, this compound serves as a valuable tool for analytical validation, instrument calibration, and detection method verification in controlled laboratory environments.

Key Features and Specifications
Chemical Name: Scopolamine
Synonyms: Hyoscine, (—)-Scopolamine, 6-beta,7-beta-epoxy-1-alphaH,5-alphaH-tropan-3-alpha-yl (S)-tropate, Scopolamine base
CAS Number: 51-34-3 (base); 114-49-8 (hydrobromide salt)
Molecular Formula: C17H21NO4
Molecular Weight: 303.35 g/mol
Purity: Greater than or equal to 98 percent by HPLC for analytical reference standards
Physical Form: White to off-white crystalline powder or colorless to white crystals
Solubility: Soluble in ethanol, methanol, DMSO, chloroform, and water; freely soluble in organic solvents
Storage Conditions: Store at 2 to 8 degrees Celsius or minus 20 degrees Celsius in airtight, light-resistant container under inert atmosphere
Stability: Stable when stored properly; protect from moisture, light, heat, and oxidation; hygroscopic material
Analytical Data: UV absorption maximum at approximately 220 nm and 258 nm; identity confirmed by NMR, LC-MS, and FTIR spectroscopy; melting point range 59 to 63 degrees Celsius (base); 195 to 199 degrees Celsius (hydrobromide)

Applications

This product is intended exclusively for laboratory research and forensic analytical applications. Legitimate use cases include: development and validation of LC-MS, GC-MS, and HPLC analytical methods for tropane alkaloid detection; forensic toxicology reference material for identification and quantification of anticholinergic substances in biological matrices; pharmaceutical quality control calibration for assay development and impurity profiling; academic research on muscarinic acetylcholine receptor antagonism mechanisms, analytical separation techniques, and alkaloid metabolism studies; method verification for regulatory compliance testing laboratories; botanical analysis and plant metabolite identification. This compound is utilized as an analytical reference standard in research settings investigating compound detection, metabolic pathway analysis, and instrumental analysis methodologies.

Safety and Handling

Handle only in a properly equipped chemical laboratory with appropriate engineering controls and institutional approval. Required personal protective equipment includes nitrile or chemical-resistant gloves, safety goggles or face shield, laboratory coat, and respiratory protection when handling powders. Use only within a certified chemical fume hood to minimize inhalation exposure. Avoid skin contact, eye contact, and ingestion. This compound is highly potent and may cause severe adverse effects at low concentrations. Anticholinergic compounds require strict handling precautions to prevent accidental exposure. In case of contact, flush affected area with water for at least 15 minutes and seek immediate medical attention. Store separately from oxidizing agents, strong acids, bases, and light sources. Dispose of waste according to institutional hazardous chemical protocols and local environmental regulations. Refer to the Safety Data Sheet (SDS) for comprehensive hazard classification, first aid measures, fire-fighting procedures, and emergency response information.

Regulatory and Compliance Information

Scopolamine is a regulated substance in numerous jurisdictions worldwide. In the United States, it is not a controlled substance under the Controlled Substances Act but is subject to prescription drug regulations under the FDA. In the United Kingdom, it is regulated as a prescription-only medicine. In Canada, it is listed under Schedule I of the Food and Drugs Act as a prescription drug. In the European Union, it is subject to pharmaceutical regulations and may be restricted in certain countries. Scopolamine is also monitored under international drug control conventions as a precursor or regulated substance in some jurisdictions. Researchers and purchasers are solely responsible for verifying compliance with all applicable local, state, national, and institutional regulations prior to ordering, possessing, importing, or using this material. Appropriate licenses, permits, and institutional approvals may be required. This product is not approved for over-the-counter sale, diagnostic use, therapeutic applications outside of prescribed medical contexts, veterinary use without authorization, or human consumption purposes.

Compliance Disclaimer
This product is sold exclusively for legitimate laboratory research, forensic analytical applications, and pharmaceutical quality control by qualified scientific personnel at accredited institutions with appropriate regulatory authorization. It is not intended for human or veterinary use, diagnostic procedures, therapeutic applications, recreational use, household use, cosmetic formulations, or any purpose involving administration to living organisms outside of approved research protocols. Purchasers affirm that they will use this material in strict compliance with all applicable laws, regulations, licensing requirements, and institutional policies governing research chemicals in their jurisdiction. The supplier disclaims all liability for misuse, unauthorized applications, illegal distribution, or non-compliant handling of this product. Researchers must obtain all necessary institutional approvals, ethics committee clearances, and regulatory permits prior to use. This compound is provided solely as an analytical reference standard for method development, validation, forensic investigation, and scientific research purposes only. Physiological effects, dosing information, and administration protocols are not provided and should not be inferred from this analytical reference material.