Xylazine

Xylazine Analytical Reference Standard

A selective alpha-2 adrenergic receptor agonist reference material, chemically designated as N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, supplied exclusively for laboratory research, forensic analysis, and pharmaceutical quality control applications. Xylazine Analytical Reference Standard | CAS 7361-61-7 | Pharmaceutical Reference Material for Laboratory Research

What is Xylazine

Xylazine is a synthetic thiazine derivative and potent alpha-2 adrenergic receptor agonist, with the molecular formula C12H16N2S and a molar mass of 220.33 g/mol. This analytical reference standard is supplied for legitimate scientific research applications including chromatographic method development, forensic toxicology screening, pharmaceutical quality control analysis, and veterinary pharmacology reference studies. As a characterized reference material, this compound serves as a valuable tool for analytical validation, instrument calibration, and detection method verification in controlled laboratory environments.

Key Features and Specifications
Chemical Name: Xylazine
Synonyms: N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine, 2-(2,6-dimethylphenylamino)-5,6-dihydro-4H-thiazine, Xylazine base, Rompun, Sedazine
CAS Number: 7361-61-7 (base); 23076-35-9 (hydrochloride salt)
Molecular Formula: C12H16N2S
Molecular Weight: 220.33 g/mol
Purity: Greater than or equal to 98 percent by HPLC for analytical reference standards
Physical Form: White to off-white crystalline powder
Solubility: Soluble in ethanol, methanol, DMSO, chloroform, and acetone; sparingly soluble in water (base form); freely soluble in water as hydrochloride salt
Storage Conditions: Store at 2 to 8 degrees Celsius or minus 20 degrees Celsius in airtight, light-resistant container under inert atmosphere
Stability: Stable when stored properly; protect from moisture, light, heat, and oxidation
Analytical Data: UV absorption maximum at approximately 220 nm and 270 nm; identity confirmed by NMR, LC-MS, and FTIR spectroscopy; melting point range 140 to 144 degrees Celsius (hydrochloride)

Applications

This product is intended exclusively for laboratory research and forensic analytical applications. Legitimate use cases include: development and validation of LC-MS, GC-MS, and HPLC analytical methods for alpha-2 adrenergic agonist detection; forensic toxicology reference material for identification and quantification of sedative substances in biological matrices; pharmaceutical quality control calibration for assay development and impurity profiling; academic research on adrenergic receptor pharmacology, analytical separation techniques, and drug metabolism studies; method verification for regulatory compliance testing laboratories; veterinary pharmaceutical reference standards for analytical method development. This compound is utilized as an analytical reference standard in research settings investigating compound detection, metabolic pathway analysis, and instrumental analysis methodologies.

Safety and Handling

Handle only in a properly equipped chemical laboratory with appropriate engineering controls and institutional approval. Required personal protective equipment includes nitrile or chemical-resistant gloves, safety goggles or face shield, laboratory coat, and respiratory protection when handling powders. Use only within a certified chemical fume hood to minimize inhalation exposure. Avoid skin contact, eye contact, and ingestion. This compound is a potent sedative and may cause central nervous system depression, bradycardia, and hypotension. Alpha-2 adrenergic agonist compounds require strict handling precautions to prevent accidental exposure. In case of contact, flush affected area with water for at least 15 minutes and seek immediate medical attention. Store separately from oxidizing agents, strong acids, bases, and light sources. Dispose of waste according to institutional hazardous chemical protocols and local environmental regulations. Refer to the Safety Data Sheet (SDS) for comprehensive hazard classification, first aid measures, fire-fighting procedures, and emergency response information.

Regulatory and Compliance Information

Xylazine is a regulated substance in numerous jurisdictions worldwide. In the United States, it is not classified as a controlled substance under the Controlled Substances Act but is subject to veterinary prescription drug regulations and is monitored by the Drug Enforcement Administration (DEA) due to emerging public health concerns. In the United Kingdom, it is regulated as a prescription-only veterinary medicine. In Canada, it is listed as a prescription drug under the Food and Drugs Act. In the European Union, it is subject to veterinary pharmaceutical regulations. Xylazine is increasingly monitored under emerging drug warning systems in multiple jurisdictions due to its presence in non-pharmaceutical supply chains. Researchers and purchasers are solely responsible for verifying compliance with all applicable local, state, national, and institutional regulations prior to ordering, possessing, importing, or using this material. Appropriate licenses, permits, and institutional approvals may be required. This product is not approved for over-the-counter sale, diagnostic use, therapeutic applications outside of prescribed medical or veterinary contexts, recreational use, or human consumption purposes.

Compliance Disclaimer
This product is sold exclusively for legitimate laboratory research, forensic analytical applications, and pharmaceutical quality control by qualified scientific personnel at accredited institutions with appropriate regulatory authorization. It is not intended for human or veterinary use outside of approved research protocols, diagnostic procedures, therapeutic applications, recreational use, household use, cosmetic formulations, or any purpose involving administration to living organisms without proper authorization. Purchasers affirm that they will use this material in strict compliance with all applicable laws, regulations, licensing requirements, and institutional policies governing research chemicals in their jurisdiction. The supplier disclaims all liability for misuse, unauthorized applications, illegal distribution, or non-compliant handling of this product. Researchers must obtain all necessary institutional approvals, ethics committee clearances, and regulatory permits prior to use. This compound is provided solely as an analytical reference standard for method development, validation, forensic investigation, and scientific research purposes only. Physiological effects, dosing information, and administration protocols are not provided and should not be inferred from this analytical reference material.